A 77636 hydrochloride

CAS No. 145307-34-2

A 77636 hydrochloride( A77636 hydrochloride )

Catalog No. M27461 CAS No. 145307-34-2

A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    A 77636 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM).
  • Description
    A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM). A-77636 hydrochloride shows antiparkinsonian activity. A-77636 hydrochloride is functionally inactive at dopamine D2 receptor.(In Vivo):A-77636 (0.1-1 mg/kg) exerts a suppressant effect on food intake in male hooded rat, due principally to a reduction in meal size and duration.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male hooded ratDosage:0.1, 0.3 and 1.0 mg/kg Administration:S.c.Result:Exerted a suppressant effect on food intake, due principally to a reduction in meal size and duration.
  • Synonyms
    A77636 hydrochloride
  • Pathway
    GPCR/G Protein
  • Target
    Dopamine Receptor
  • Recptor
    Free radical scavengers|Platelet aggregation
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    145307-34-2
  • Formula Weight
    365.89
  • Molecular Formula
    C20H28ClNO3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(N)[C@@H]1O[C@H]([C@@]23CC4CC(C2)CC(C3)C4)CC=5C1=CC=C(O)C5O.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zbidi H, et al. Olive tree wood phenolic compounds with human platelet antiaggregant properties. Blood Cells Mol Dis. 2009 May-Jun;42(3):279-85.
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